Sibutramine 20 mg is a Medicinal substance that is called sibutramine hydrochloridum monohydricum.
One capsule contains 20mg of this substance.
Sibutramine, together with a low-calorie diet and physical exercise, is recommended for patients with nutritional obesity. It helps to reduce body weight by inducing a feeling of satiety, even after ingesting a small amount of food.
Sibutramine is a serotonin and norepinephrine reuptake inhibitor. It works by affecting the reuptake of the neurotransmitters 5hydroxytryptamine (called serotonin) and noradrenaline into nerve cells in the brain. Neurotransmitters are chemicals that allow nerve cells to communicate with each other. By blocking their reuptake, sibutramine increases the amount of these neurotransmitters in the brain. Increased levels of neurotransmitters in the brain help patients feel fuller after eating and help reduce their food intake.
Sibutramine, along with diet and exercise, is used in very overweight patients with a body mass index (BMI) greater than or equal to 30kg/m2 and in overweight patients with a BMI greater than or equal to 27kg/m2 who also have risk factors associated with obesity, such as type II diabetes or dyslipidaemia (abnormal blood fat levels).
It does not have addictive or psychostimulant effects.
Adverse effects occur predominantly at the start of treatment during the first 4 weeks. Their frequency decreases with time. As a rule, they are not serious, do not lead to discontinuation of treatment and are transient. Side effects include increased blood pressure, palpitations, dry mouth, constipation and headache.
One Sibutramine 20mg capsule is taken once daily in the morning and should be taken with sufficient fluid